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ISSN 2959-1864 (Online); ISSN 2958-0536 (Print); DOI: 10.30546/abc
Acta Botanica Caucasica

PHYTOCHEMISTRY, TRADITIONAL USES AND PHARMACOLOGICAL POTENTIAL OF JURINEA DOLOMIAEA SUSTAINING IN HARSH ALTITUDES OF PIR PANJAL RANJE POONCH, JAMMU AND KASHMIR

Abstract
Abstract. Jurinea dolomiaea is a plant that belongs to the Asteraceae family and is native to alpine regions in Myanmar, China, India, Nepal, and Pakistan. It contains a variety of bioactive compounds such as sesquiterpene lactones, sterols, triterpenoids, saponins, tannins, flavonoids, glycosides, steroids, phenolic compounds, fixed oils, fats, terpenes, and lignans. Traditionally, this plant has been used in herbal medicine for its aphrodisiac properties and for treating rheumatism, fever, colic, gout, and puerperal fever. It is also used in the incense industry and as an insect repellent due to its pleasant aroma. Pharmacological studies have shown that J. dolomiaea has antileishmanial, antioxidant, antibacterial, antimalarial, analgesic, and hepatoprotective properties. It also has potential benefits for reproductive health and may help protect DNA. In addition, silver nanoparticles synthesized from J. dolomiaea have significant pharmacological potential. Moreover, its phytochemicals have analgesic, antinociceptive, anxiolytic, sedative, anticancer, immunomodulatory, antimicrobial, lipid-regulating, anti-inflammatory, hepatoprotective, wound-healing, respiratory-protective, antidiabetic, and antioxidant effects.
© Acta Botanica Caucasica, 2026